OPTIMAL ORGAN-SPARING INTENSITY-MODULATED RADIATION THERAPY (IMRT) REGIMEN FOR THE TREATMENT OF LOCALLY ADVANCED ANAL CANAL CARCINOMA: A COMPARISON OF CONVENTIONAL AND IMRT PLANS

Abstract Background To compare the dosimetric advantage of three different intensity-modulated radiation therapy (IMRT) plans to a three dimensional (3D) conventional radiation treatment for anal cancer with regards to organs-at-risk (OAR) avoidance, including iliac bone marrow.Methods Five patients with T1-3 N0-1 anal cancer and five with T4 and/o

Summary: The differentiation of naive CD8+ T lymphocytes into cytotoxic effector dv1433-010 and memory CTL results in large-scale changes in transcriptional and phenotypic profiles.Little is known about how large-scale changes in genome organization underpin these transcriptional programs.We use Hi-C to map changes in the spatial organization of lo

The term specific character as a specialized sign of language and raiders ornament science is considered in the article.The term is a unit of cognition and simultaneously serves as a unit of nomination of its results.The author advances an idea that, representing a special notion by means of a language sign, the term becomes cognitive semiotic inst

This paper presents an updated trend analysis of water vapour in the lower midlatitude stratosphere from the Boulder balloon-borne NOAA frostpoint hygrometer measurements and from the Halogen Occulation Experiment (HALOE).Two corrections for instrumental bias are applied to homogenise the frostpoint gfw-utl-ws250 data series, and a quality assessme

Acetaldehyde (ACD) is the first metabolite of ethanol.Although, the role of ACD in ethanol addiction has been controversial, there are data showing a relationship.The objective of the current study was further to test the hypothesis that ACD itself is reinforcing.For this reason, we carried out a study on operant oral ACD gfw-utl-ws250 self-adminis